R packages by rozen-lab

cosmicsig - Mutational Signatures from COSMIC (Catalogue of Somatic Mutations in Cancer)

A data package with 2 main package variables: 'signature' and 'etiology'. The 'signature' variable contains the latest mutational signature profiles released on COSMIC <https://cancer.sanger.ac.uk/signatures/> for 3 mutation types: * Single base substitutions in the context of preceding and following bases, * Doublet base substitutions, and * Small insertions and deletions. The 'etiology' variable provides the known or hypothesized causes of signatures. 'cosmicsig' stands for COSMIC signatures. Please run ?'cosmicsig' for more information.

Last updated 2 years ago

3.04 score 1 stars 22 scripts 231 downloads

mSigTools - Mutational Signature Analysis Tools

Utility functions for mutational signature analysis as described in Alexandrov, L. B. (2020) <doi:10.1038/s41586-020-1943-3>. This package provides two groups of functions. One is for dealing with mutational signature "exposures" (i.e. the counts of mutations in a sample that are due to each mutational signature). The other group of functions is for matching or comparing sets of mutational signatures. 'mSigTools' stands for mutational Signature analysis Tools.

Last updated 2 years ago

3.00 score 2 stars 9 scripts 202 downloads